Evaluaton of hypoglycaemic and wound healing activities of Tiliacora acuminata

Ram Mohan Manda, Vishwanath valusa, Srinivas Reddy Karka, Vamshi Krishna Parshaboina, Ganapaty Seru

Abstract


Natural products particularly plant origin have played a vital role in prevention and
mitigation of human diseases. The present study was carried to evaluate the
antihyperglycaemic and wound healing activity of the leaf Extracts of Tiliacora
acuminate (Lam) on rats, the aqueous leaf extract was found to produce significant
reduction of blood glucose concentration between 2-4 h of administration in alloxan
induced hyperglycaemic rats at tested dose levels. However, in normoglycaemic
animals, the extract at 400mg/kg produced significant reduction of blood glucose
between 2-4 h of administration. In the wound healing studies, the leaf juice was
found to be more active than the extract.

Keywords


Tiliacora acuminate, Alloxan, Wound healing, Antihyperglycaemic, Nitrofurazone.

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DOI: https://doi.org/10.30750/ijpbr.2.4.19

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