Development of Fast Disintegration Tablets As Oral Drug Delivery System-A Review.

Chiman Beri Dhanasekaran, Isha Sacher

Abstract


Fast disintegrating tablets (FDTs) have received increasing demand from the last few years and the field has become
a rapidly growing field in the pharmaceutical industry. Fast disintegrating tablets (FDTs) are those solid doses form
which when put on the tongue gets rapidly dissolved, releasing the drug within a few second without need of water.
The development of FDTs have been formulated for paediatric, geriatric and bedridden patients and for active
patients who are busy and travelling and may not have access to water. Such formulation provide an opportunity for
product line extension in the many elderly persons will have difficulties in taking conventional oral doses forms
(viz, solution suspensions tablet and capsules) because of hand tremors and dysphagia. This article focused on ideal
requirements, need for development of FDTs, challenges in formulations, suitability of drug candidates superdisintegrants
employed, various technologies developed for FDTs. Evaluation methods, and various marketed
products.

Keywords


Fast disintegrating tablets (FDTs), Solid dosage form, Conventional oral dosage form, Superdisintegrants, bioavailability, Patient’s compliance.

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DOI: https://doi.org/10.30750/ijpbr.1.3.13

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