Evaluation of antibacterial activity of macrocyclic metal complexes derived from dihydrazone and diketone

Sabir Ali, Vandna Singh

Abstract


Synthesis of macrocyclic metal complexes of Cr(III) and Fe(III) by the condensation of benzil dihydrazone with 1H-indole-2, 3-dione.The metal complexes were characterized by elemental analysis, molar conductance, magnetic susceptibility, thermal analysis, ESR, infrared, 1H NMR and UV-visible spectroscopy. On the bases of these studies, a fivecoordinate square pyramidal geometry is proposed for all the metal complexes. In vitro antibacterial activity of macrocyclic metal complexes exhibited good results.

Keywords


Antibacterial; Dihydrazone;Diketone;Macrocyclic metal complexes; Evaluation parameter.

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DOI: https://doi.org/10.30750/ijpbr.4.3.3

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