Evaluation of pharmacological potentials of the ethanolic extract of a mushroom (Ganoderma lucidum) grown in FCT.

v a Etim, S Abubakar, U K Asemota, O E Okereke, G H Ogbadu

Abstract


The aim of this research work is to evaluate the pharmacological potentials of the mushroom
Ganoderma lucidium grown in Federal Capital Territory Abuja, Nigeria. Phytochemical,
antioxidant and antibacterial properties of ethanolic extract were carried out. The
phytochemical analysis of the ethanolic extract revealed the presence of pharmacological
constituents such as: steroids, triterpenoid, carbohydrate, cardiac glycosides and glycosides
.The antibacterial activity of the extract was conducted using well agar diffusion method on
four clinical bacterial isolate which are identified using various standard biochemical tests.
The extract shows activity on: Escherichia coli (12mm), Klebsiella pneumonia (12mm),
Proteus mirabilis (13mm) and Streptococcus spp (14mm) at 1000mg/ml respectively .The
antioxidant potentiality of the extract was also evaluated using the stable radical 1,1-
Diphenyl-l-pienyl hydroxyl (DPPH) and the IC50 of the standards and extract was obtained at
0.06, 0.13, and 0.23 respectively.

Keywords


Antibacterial, Antioxidant, Ethanolic extract, Ganoderma lucidum, Phytochemical.

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DOI: https://doi.org/10.30750/ijpbr.2.1.1

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