Novel study in fast dissolving drug delivery system: a review

Abstract

Novel drug delivery systems are becoming increasingly sophisticated as pharmaceutical scientists acquire a better understanding of the physicochemical and bio-chemical parameters pertinent to their performance. Despite tremendous advancements in drug delivery, the oral route remains the perfect route for the administration. Novel drug delivery system assists to achieve better patient compliance. Fast dissolving tablets are one of them.FDT have benefits such as accurate dosing, easy portability and manufacturing, good physical and chemical stability and an ideal alternative for pediatric and geriatric patients. FDDT formulation combines the advantage of both liquid and conventional tablet formulation while also offering advantage over both traditional dosage forms. Some tablets are designed to dissolve in saliva remarkably fast, within a few seconds, and are true fast- dissolving tablets. Others contain agents to enhance the rate of tablet disintegration in the oral cavity, and are more appropriately termed fast-disintegrating tablets, as they may take up to a minute to completely disintegrate.