A Recent Approach for Developing an Anti-malarial Phytomedicine

Abstract

A reverse pharmacology approach to developing an anti-malarial phytomedicine is designed and implemented in Mali resulting in a new standardized herbal anti-malarial after six years of research. The first step is to select the remedy for development through a retrospective treatment. The second step is the dose-escalating clinical trial that showed a dose-response phenomenon and help the safe and most effective dose. The third step is to compare the phytomedicine in the first line treatment. The fourth step is to identify the active compound can used for standardization and quality control.