Evaluaton of hypoglycaemic and wound healing activities of Tiliacora acuminata

Abstract

Natural products particularly plant origin have played a vital role in prevention and mitigation of human diseases. The present study was carried to evaluate the antihyperglycaemic and wound healing activity of the leaf Extracts of Tiliacora acuminate (Lam) on rats, the aqueous leaf extract was found to produce significant reduction of blood glucose concentration between 2-4 h of administration in alloxan induced hyperglycaemic rats at tested dose levels. However, in normoglycaemic animals, the extract at 400mg/kg produced significant reduction of blood glucose between 2-4 h of administration. In the wound healing studies, the leaf juice was found to be more active than the extract.