Synthesis and microbial screening of 6-pyridin-4-yl-2, 3-dihydro-1Hpyridazin-4-one derivatives

Authors

  • Athar Javed Govt. College of Pharmacy, Rohru, Shimla, H. P. India.
  • M. S. Bhatia Govt. College of Pharmacy, Rohru, Shimla, H. P. India.
  • Mayuresh Shinde Govt. College of Pharmacy, Rohru, Shimla, H. P. India.
  • Vinod Singh Govt. College of Pharmacy, Rohru, Shimla, H. P. India.

Abstract

6-pyridin-4-yl-2, 3-dihydro-1H-pyridazin-4-one derivatives were synthesized by a simple method. The isonicotinic acid hydrazide was made to react with acetaldehyde and acetone. This results into the formation of the respective hydrazones. These hydrazones formed were cyclized to the pyridazine derivatives. All synthesized compounds were subjected to antimicrobial activity.

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Published

2013-09-30

How to Cite

1.
Javed A, Bhatia MS, Shinde M, Singh V. Synthesis and microbial screening of 6-pyridin-4-yl-2, 3-dihydro-1Hpyridazin-4-one derivatives. IJPBR [Internet]. 2013Sep.30 [cited 2026Aug.23];1(03):01-7. Available from: https://ijpbr.in/index.php/IJPBR/article/view/819