Comparison between the conventional method and molecular line probe assay for identification and drug sensitivity of mycobacteria tuberculosis from clinical specimens

Authors

  • Ritu Kansal Department of Microbiology, Subharti Medical College, Meerut (U.P.), India
  • Molly Madan Department of Microbiology, Subharti Medical College, Meerut (U.P.), India
  • Richa Kansal Department of Microbiology, Subharti Medical College, Meerut (U.P.), India
  • Vivek Agwan Department of Microbiology, Subharti Medical College, Meerut (U.P.), India
  • Isha Bansal Department of Microbiology, Subharti Medical College, Meerut (U.P.), India
  • Nivesh Agrawal Department of Microbiology, Subharti Medical College, Meerut (U.P.), India

DOI:

https://doi.org/10.30750/ijpbr.2.3.13

Abstract

Rapid susceptibility testing of Mycobacterium tuberculosis strains is imperative for therapy selection but traditional drug susceptibility tests take weeks or are expensive. Classical drug susceptibility (DST) may take up to 2 to 4 months. The line probe assay is a commercially available line-probe assay that rapidly detects Mycobacterium tuberculosis (MTB) complex, as well as the most common mutations associated with rifampicin and isoniazid. In this study we assessed the sensitivity and specificity of the rapid molecular method in comparison with the conventional method.

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Published

2014-09-30

How to Cite

1.
Kansal R, Madan M, Kansal R, Agwan V, Bansal I, Agrawal N. Comparison between the conventional method and molecular line probe assay for identification and drug sensitivity of mycobacteria tuberculosis from clinical specimens. IJPBR [Internet]. 2014Sep.30 [cited 2026Jul.11];2(03):80-3. Available from: https://ijpbr.in/index.php/IJPBR/article/view/847

Issue

Vol. 2 No. 03 (2014): Indian Journal of Pharmaceutical and Biological Research

Section

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