Simultaneous Spectrophotometric Estimation of Telmisartan and Amlodipine Besylate in Tablet Dosage Form

Authors

  • N. K. Gupta NIMS Institute of Pharmacy, NIMS University, Jaipur, 303121, Rajasthan, India
  • A. Peepliwal NIMS Institute of Pharmacy, NIMS University, Jaipur, 303121, Rajasthan, India
  • D. S. Rathore NIMS Institute of Pharmacy, NIMS University, Jaipur, 303121, Rajasthan, India
  • P. Gupta NIMS Institute of Pharmacy, NIMS University, Jaipur, 303121, Rajasthan, India

DOI:

https://doi.org/10.30750/ijpbr.3.3.8

Keywords:

Amlodipine Besylate (AML), Telmisartan (TEL), Simultaneous equation method (SEM).

Abstract

A simple, accurate and reproducible spectrophotometric methods have been developed for the simultaneous estimation of Telmisartan (TEL) and Amlodipine Besylate (AML) in combined tablet dosage forms. The method involves determination using the simultaneous equation method, the sampling wavelengths selected are ‘TLM’ = 297nm.and ‘AML’ =238nm., over the concentration ranges of 8-48μg/ml for ‘TEL’ and 1-6 μg/ml for ‘AML’ respectively. The method was validated for linearity, accuracy, precision, robustness and application for assay as per ICH guidelines. The proposed method is simple, economical, accurate and precise, and could be successfully employed in routine quality control for the simultaneous analysis of Telmisartan (TEL) and Amlodipine Besylate (AML).

Downloads

Published

2015-09-30

How to Cite

1.
Gupta NK, Peepliwal A, Rathore DS, Gupta P. Simultaneous Spectrophotometric Estimation of Telmisartan and Amlodipine Besylate in Tablet Dosage Form. IJPBR [Internet]. 2015Sep.30 [cited 2026Jul.27];3(03):50-4. Available from: https://ijpbr.in/index.php/IJPBR/article/view/871

Issue

Vol. 3 No. 03 (2015): Indian Journal of Pharmaceutical and Biological Research

Section

Table of Content