In-silico designing of NKK: A better ligand than Aciclovir against Herpes Simplex Virus

Authors

  • Neelabh . Department of Zoology, Mahila Mahavidyalaya, Banaras Hindu
  • K. K. Jeswara Centre for Botanical Research , The Madura College, Madurai. T.N., India.
  • A. Kumari Centre for Botanical Research , The Madura College, Madurai. T.N., India.
  • K. Singh Centre for Botanical Research , The Madura College, Madurai. T.N., India.

DOI:

https://doi.org/10.30750/ijpbr.3.1.8

Keywords:

Aciclovir, Herpes Simplex Virus, in-silico, thymidine kinase

Abstract

Aciclovir is the best dr thymidine kinase made by the HSV. In the current study we have successfully designed a drug candidate “NKK”, which is far more efficient than aciclovir in terms of binding energy and physiochemical properties again used softwares viz. Autodock 4.0, FireDock and Hex dock in order to demonstrate that “NKK” is a better ligand than aciclovir with respect to aforesaid properties.

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Published

2015-03-31

How to Cite

1.
. N, Jeswara KK, Kumari A, Singh K. In-silico designing of NKK: A better ligand than Aciclovir against Herpes Simplex Virus. IJPBR [Internet]. 2015Mar.31 [cited 2026Jul.14];3(01):48-55. Available from: https://ijpbr.in/index.php/IJPBR/article/view/934

Issue

Vol. 3 No. 01 (2015): Indian Journal of Pharmaceutical and Biological Research

Section

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