Formulation, Physical Characteristics, and Irritation Test of Soothing Gel Combination from Aloe vera gel and Dragon Fruit Juice

Abstract

Dry skin is often causes of several problems in skin health. People pay less attention to symptoms caused such as redness, roughness, scaling, cracking, and itching. Factors that cause dry skin include temperature, air humidity, and exposure to ultraviolet light. Soothing gel that contains of high concentration active ingredients is one of cosmetic products that are trending in Korea. In this study, the combination of aloe (Aloe vera) and dragon fruit (Hylocereus polyrhizus) was used as active ingredients. The aim of this study was to determine the phytochemical screening of active ingredients, physical characteristic, and measuring irritation index on animal test. Formulation of soothing gel preparation was made by varying concentration of active inggredients, that is, FI (85%), FII (90%), and FIII (95%). The data obtained were analyzed by statistical with a different 95% confidence level a significant difference between treatment groups. Phytochemical screening confirmed the presence of alkaloid, flavonoid, terpenoid, and saponin (negative results in dragon fruit juice) in each juice. The result of physical characteristic showed that the concentration of active ingredient affect pH, spreadability, and adhesion power (P < 0.05). Meanwhile, the result of measuring irritation index was showed that none of the formulas caused erythema and edema at 24, 48, and 72 h observed time.
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