Clinical Profile and Hormonal Patterns in Women with Newly Diagnosed PCOD Attending a Tertiary Care Hospital

Abstract

Background: Polycystic ovarian disease is an endocrine condition of hormonal imbalance, irregular menstrual periods, and high androgen levels and is the most common endocrine disease in women of reproductive age. It commonly presents with metabolic derangements such as insulin resistance, obesity and dyslipidaemia, which may cause infertility and raise the risk of diabetes and cardiovascular disease in the long run.
Objective: To evaluate the clinical profile and hormonal patterns in newly diagnosed PCOD patients.
Methods: This cross-sectional study was conducted at PMCH, Patna, from September 2025 to February 2026, including 200 women diagnosed with PCOD. Clinical features, BMI, and hormonal parameters (LH, FSH, testosterone, prolactin) were assessed. Statistical analysis included chi-square test and t-test, with p<0.05 considered significant.
Results: The majority of patients were either overweight or obese (70%). The most prevalent symptom was irregular menstruation (70%). Increased LH levels were detected in 65% of patients and increased testosterone levels in 55% of individuals. BMI was significantly associated with hormonal imbalance (P<0.05).
Conclusion: PCOD is strongly associated with obesity and hormonal disturbances. Early diagnosis and lifestyle modification are crucial for management.